ChemNet > CAS > 126-07-8 Griseofulvin

126-07-8 Griseofulvin

product Name	Griseofulvin
CAS No	126-07-8;78739-00-1
Synonyms	grisovin; 7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione; (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione; (2R,6'S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione; (2S,6'S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione; (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohexane]-3,4'-dione; Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione,7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'R-trans)-; (+)-Griseofulvin
Molecular Formula	C₁₇H₁₉ClO₆
Molecular Weight	354.7822
InChI	InChI=1/C17H19ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h7-8,12H,5-6H2,1-4H3/t8-,12?,17+/m1/s1
EINECS	204-767-4
Molecular Structure
Density	1.35g/cm³
Melting point	217-224℃
Boiling point	527.9°C at 760 mmHg
Refractive index	1.565
Flash point	205.9°C
Water solubility	practically insoluble
Vapour Pressur	3.11E-11mmHg at 25°C
Hazard Symbols	T:Toxic;
Risk Codes	R60:; R61:; R40:; R43:;
Safety Description	S53:; S22:; S36/37/39:; S45:;

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Description	Product Information Product Name: Griseofulvin Cas No.: 126-07-8 Molecular Formula: C17H17ClO6 Molecular Weight: 352.77 Uses: Griseofulvin is used to treat skin infections such as jock itch, athlete's foot, and ringworm; and fungal infections of the scalp, fingernails, and toenails. Specification: Test items Specifications (BP2011 /EP7.0) Description A white or yellow white microfine powder Identification A: IR B:Colour test (a white-red colour develops) Acidity Not more than 1.0ml of 0.02M sodium hydroxide is required. Solubility Practically insoluble in water,freely soluble in dimethyl formamide and in tetrachloroethane,slightly soluble in ethanol and in methanol. Specific optical rotation Calculated with reference to the dried substance +354??~+364?? Particle size 95% no more than 5um(larger particles which may occasionally exceed 30um) Melting point It melts at about 220?? Appearance of solution The solution is clear Not more intensely coloured than reference solution Y4 Relate...
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