b-chlorophenetole

• Category :

  Intermediates/Pharmaceutical intermediates

• Synonyms :

  Benzene, (2-chloroethoxy)-;2-chloroethyl phenyl ether;

• CAS NO :

  622-86-6

• EC NO :

  210-757-0

• Molecular Formula :

  C₈H₉ClO

• Molecular Weight :

  156.6095

• Main Specifications :

  99% min

• InChI :

  InChI=1/C8H9ClO/c9-6-7-10-8-4-2-1-3-5-8/h1-5H,6-7H2

• Packing :

  25kg，50kg 200kg

• Product description :

  What is the chemical of b-chlorophenetole? Appearance: Colorless to pale yellow transparent oily liquid ; Assay：99%min by GC ; IR Identity: conform to standard ; HNMR： conform to standard ; carbon spectrum: conform to standard ; Water by K. F.:0.5% max or as per the customer’s request ; Loss on drying:0.5% max. or as per the customer’s request ; boiling point: 217–220 °C ; ======================================================================== main purpose As a pharmaceutical intermediate, used for synthesizing the following drugs: The anthelmintic insecticide Miechon Ning; Antidepressant naphthoprim. Can react with dimethyl-amine to produce the intermediate phenoxyethyldimethyl-amine. ========================================================================= synthetic route Mainly prepared through the following two methods: 1. Phenol reacts with dichloroethane under high pressure conditions: Mix phenol, sodium hydroxide solution, and water to form sodium phenolate; Add dichloroethane and react for 3 hours at 130 ° C and 0.75-0.88 MPa; After the reaction, cool, wash, layer, evaporate the solvent, and distill to obtain the product. 2. Reaction of o-chlorophenol with diethyl sulfa

• Uses :

  As a pharmaceutical intermediate, used for synthesizing the following drugs

• Molecular Structure :