2-Methoxy pyridine

• Category :

  Organic chemicals and Derivatives/Aroma compounds

• Synonyms :

  Methyl 2-pyridyl ether;2-methoxy pyridine;

• CAS NO :

  1628-89-3

• EC NO :

  216-623-8

• Molecular Formula :

  C₆H₇NO

• Molecular Weight :

  109.1259

• Main Specifications :

  99% min

• InChI :

  InChI=1/C6H7NO/c1-8-6-4-2-3-5-7-6/h2-5H,1H3

• Packing :

  25kg，50kg 200kg

• Product description :

  What is the chemical of 2-Methoxy pyridine? Appearance: Colorless to pale yellow transparent liquid ; Assay：99%min by GC ; IR Identity: conform to standard ; HNMR： conform to standard ; carbon spectrum: conform to standard ; Water by K. F.:0.5% max or as per the customer’s request ; Loss on drying:0.5% max. or as per the customer’s request ; ============================================================================= Usage: 2-methoxypyridine is mainly used as an intermediate in organic synthesis, especially in the pharmaceutical industry and spice synthesis. It can be used to prepare other pyridine derivatives, such as 6-methoxy-3-pyridinecarboxaldehyde, etc ============================================================================== Synthetic route 2-Methoxypyridine can be prepared by three main methods: Synthesis method Reaction conditions Key reagents Literature support Nucleophilic substitution method Copper salt catalysis, heating 2-halopyridine + sodium methoxide Reductive methoxylation method Magnesium powder/methanol system 2-halopyridine + Mg/CH?OH Palladium catalyzed coupling method Pd catalyst, Suzuki type reaction 2-halopyridine + methoxyboronate Note: In industry, the nucleophilic substitution method is preferred because of its low cost and high yield (>85%).

• Uses :

  used as an intermediate in organic synthesis

• Molecular Structure :