Decoquinate

• Category :

  Food and Feed additives

• Synonyms :

  Deccox;Ethyl 6-decyloxy-7-ethoxy-4-hydroxy-3-quinolinate;ethyl 6-(decyloxy)-7-ethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate;

• CAS NO :

  18507-89-6

• EC NO :

  242-389-1

• Molecular Formula :

  C₂₄H₃₅NO₅

• Molecular Weight :

  417.5384

• Main Specifications :

• InChI :

  InChI=1/C24H35NO5/c1-4-7-8-9-10-11-12-13-14-30-21-15-18-20(16-22(21)28-5-2)25-17-19(23(18)26)24(27)29-6-3/h15-17H,4-14H2,1-3H3,(H,25,26)

• Product description :

  Specification	Packing
  Pure	25kg/drum
  Premix 6%	25KG/BAG

  
  Safety: the only chemical coccidiostat that authorized to use by Japan , EU, US and China government in the world.
  Validity: Applied in China , in where it is new coccidiostat . No resistance.
  Better Choice : ideal substituted medicine for anti coccidia , growth promotion, and color improvement.
  Yaqiu:
  Decoquinate premix 6%. It is used for preventing and curing poultry coccidiosis of E.Tenella , E.maxima , E.acervulina , E.necatrix , E.brunetti , E.mivati .
  It comes into effect in the early period of coccidia life, and its effective duration is the longest.
  Usage strength: 20-40ppm.
  Characteristics:
  Yaqiu is high efficient chem.ical coccidiostat which contents 6% Decoquinate .
  Appendix 1: molecular structure of Decoquinate

  

  Mechanism:The drug acts on the agamogenesis phase of coccidia . Yaqiu stops the propagation of coccidia spores by interfering DNA synthesis after it enters into the daughter archespores. Yaqium comes into effect in the early stage of coccidia life. Hence, it can avoid the damage of poultry intestine, which can help farmers gain higher economic profit.
  Appendix 2: Coccidia life history

  

  Appendix 3: Different coccidiostat on different stage of coccidia life.

  

  Effect:
  Unique function mechanism enable Yaqiu has excellent anti coccidian and growth promoted effect.
  Appendix 4: Test result of different coccidiostat on chicken coccidia .

  
  Form 1: Test result of Decoquinate

  Item	Decoquinate (40ppm)	Decoquinate (30ppm)	Decoquinate (20ppm)	Maduramicin (5ppm)	White control group	Red control group
  Bloody stool	0	0	0	0	0	+4
  Lesion	0	0	0	0	0	+4
  Lesion data	0	0	0	0	0	40
  Fecal ovary date(x102)	0	0	0	2.67	0	2304
  Cecum ovarydate(x104)	0	0	0	0.37	0	3633.3
  Ovary data	0	0	0	0	0	40
  Anti coccidian ( ACI )	198.63	19x3.59	191.57	191.38	200	106.18

  Safety:
  Poultry: 800ppm in feed (26times of normal dosage), continous for 127days. No poisoning.
  Calf: continous feed 10day at 20mg per Kg avoirdupois (40times of normal dosage). No poisoning.
  Sheep: feed at 4mg per kg avoirdupois (8times of normal dosage). No poisoning.
  Goat: continous feed 84days at 0.5mg per Kg avoirdupois (10times of recommended dosage). No poisoning.
  Swine: contious feed 10days at 800ppm. No poisoning.
  Fish: Mixed in feed in the proportion of 20%, continous use 2 weeks. No poisoning.

  Stability:
  Yaqiu can keep steady for 4years under fitting temperature and humidity.
  Prescription of taking chemical coccidiostat as feed additives in different countries:

  Coccidiostat	Japan	EU	USA	China
  ( Decoquinate )	+(7days)	+ ( 3days )	+ ( 0days )	+ ( 5 days )
  ( Robenidine Hydrochloride)	-	+ ( 5days )	+ ( 5days )	+ ( 5 days )
  ( Diclazuril )	-	+ ( 5days )	+ ( 0days )	+ ( 5 days )
  ( Nicarbazin )	+ ( 7days )	-	+ ( 4days )	+ ( 4 days )
  ( Clopidol )	-	-	+ ( 5 days )	+ ( 5 days )
  ( Dinitolmide )	-	-	-	+ ( 3 days )

  “+”allow to usd “-”prohibit from using Numbers in bracket is withdrawal time.
  
  Usage:
  Chicken: add 453g Yaqiu or 20-40ppm in each ton feed.
  Cattle, sheep: mixing uniformly 215 -1513g Yaqiu in each ton feed.
  It is prohibited during laying period. Not mix with feed containing bentonite .
  Withdrawal period: 5days.

  Compatibility:No incompatiblity at all with other allowed medicated feed additives.

  Packing: 20kg /drum 25kg/drum
  Content: 60g Decoquinate in per kilogram Yaqiu .
  Storage:Store in dry and shady place and keep the packing airtight.
  Shelf-life: 3 years.
  pathological changes data ovary data
  monensin Salinomycin narasin Maduramicin Semduramicin Yaqiu No medication to infection No medication no infection.

• Molecular Structure :