2-Methylthiazole
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- Category :
Organic chemicals and Derivatives/Aroma compounds
- CAS NO : 3581-87-1
- EC NO : 222-702-8
- Molecular Formula : C4H5NS
- Main Specifications : 99% min
- Synonyms : 2-methyl-1,3-thiazole;
Package: 25kg，50kg 200kg
Uses : used as an edible essence
Molecular Structure:
Product description:
What is the chemical of 2-Methylthiazole ?
Appearance: Colorless to pale yellow transparent liquid ;
Assay：99%min by GC ;
IR Identity: conform to standard ;
HNMR： conform to standard ;
carbon spectrum: conform to standard ;
Water by K. F.:0.5% max or as per the customer’s request ;
Loss on drying:0.5% max. or as per the customer’s request ;
Melting point: -24 °C;
boiling point: 128.5 ° C to 129 ° C (at 760 mmHg pressure);
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Use: The compound is mainly used as an edible essence, with green vegetable aroma, and is widely used in food essence formulations. In addition, it is also an important intermediate in organic synthesis, used for the preparation of other heterocyclic compounds or fine chemicals
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Synthesis route: The detailed synthesis steps of 2-methylthiazole are not clearly provided in the public information. But according to its structure (with methyl substitution at the 2-position of the thiazole ring), its synthesis can usually be achieved through the following general methods:
Hantzsch thiazole synthesis method: It involves the reaction of alpha halogenated ketones (such as chloroacetone) with thiourea or thioacetamide, followed by cyclization dehydration to produce 2-methylthiazole.
Derived from 2-aminothiazole: prepared by methylation reaction of 2-aminothiazole.
Other methods include reduction after reaction of alpha thiocyanate methyl ester with hydrogen chloride, or condensation of acetamide with acetone chloride after reaction with phosphorus pentasulfide.
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