2-Isopropyl-4-methylthiazole
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- Category :
Organic chemicals and Derivatives/Aroma compounds
- CAS NO : 15679-13-7
- EC NO : 239-758-4
- Molecular Formula : C7H11NS
- Main Specifications : 99% min
- Synonyms : 2-Isopropyl-4-methyl thiazole;THIAZOLE, 4-METHYL-2-(1-METHYLETHYL)-; ;4-methyl-2-(propan-2-yl)-1,3-thiazole;
Package: 25kg，50kg 200kg
Uses : Mainly used for the preparation of essence
Molecular Structure:
Product description:
What is the chemical of 2-Isopropyl-4-methylthiazole ?
Appearance: Colorless to light yellow liquid with vegetable and nut like aroma;
Assay：99%min by GC ;
IR Identity: conform to standard ;
HNMR： conform to standard ;
carbon spectrum: conform to standard ;
Water by K. F.:0.5% max or as per the customer’s request ;
Loss on drying:0.5% max. or as per the customer’s request ;
boiling point: 92 ° C at 50 mmHg pressure;
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Usage: Mainly used for the preparation of essence, such as peach, mango, passion fruit and other fruit essence, as well as meat and tobacco essence.
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Synthetic Routes
Industrially, the following two efficient synthetic routes are mainly used:
**Nucleophilic Substitution Method (Mainstream Process)**
Reagents: 4-Methylthiazole + 2-Bromopropane
Catalyst: Potassium carbonate (K?CO?)
Reaction Conditions: 80–90°C, in a polar aprotic solvent (such as acetonitrile or DMF) for 4–6 hours
Product Purity: Up to 98% or higher; simple post-processing; suitable for large-scale production.
**Condensation Cyclolation Method (Laboratory Alternative)**
Reagents: α-Keto Acid + Aminothiourea
Steps: First construct the thiazole ring, then introduce the isopropyl group via alkylation.
Advantages: Suitable for structural derivatization studies, but the steps are more complex and the yield is lower.
If you are sourcing 2-Isopropyl-4-methylthiazole from China ,just feel free to inquire
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